Our experimental set-up for the acquisition of fMRI data

All MS Patients were :

  • Between 20 to 50 years old
  • With disease diagnosis less than 5 years and (With various number of attacks)
  • Expanded Disability Status Scale (EDSS) score under 3.5
  • Right-handed
  • With the definite diagnosis relapsing-remitting MS (RRMS), determined by the Revised McDonald criteria
  • Not be in attack phase during the experimental procedure, or it had to be at least three weeks after their last hospitalization

Control subjects were :

  • Between 20 to 50 years old
  • Right-handed

Data Collecting – Achieved Data from each Subject

NOTE:
  • All patients were selected with the consulting of neurologists.
  • Complete clinical characteristics of patients provided to us before the experiment by neurologist, hospital, or any institution involved.
  • An informed consent was taken from each subject
  • All Patient selection were accompanied by a neurologist
  • For each patient, a neuropsychological evaluation session was holded by our psychologist to assess the status of a wide range of patients’ cognitive functions such as working memory, attentional skills, and speed of information processing
  • The designed cognitive task was explained to the subjects , they were trained how to do and respond, and then our team practiced cognitive tasks by participants in a quiet room with a separate and exclusive computer
  • Functional Magnetic Resonance Imaging (fMRI) scanning under the determined cognitive task Neuropsychological evaluation, cognitive tasks designing, screening all electrical equipment, and acquisition of fMRI data are based on selected or designed methods by NBNZ CAD that are performed by members of this group.
Menu